naltrexone 25 mg half life
Oral naltrexone has been used to treat opioid dependence for many years and has been approved to treat alcohol use disorders AUDs since 1994. The terminal half-life ranges from three hours after intravenous administration to 28 to 37 hours after sublingual administration.
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10 It is unclear why there is such a difference in half life depending on the route of administration but.
. 29 vs 5 in the outpatient condition. Naltrexone hydrochloride is a relatively pure and long-lasting opioid antagonist. Doctors gave naltrexone to opioid addicts in recovery to prevent relapse.
The dosage needed to achieve opioid blockage is high ranging from 50 100 mgday 1 6. Naltrexone approved in US to treat opioid dependence. By blocking all receptors in advance naltrexone renders narcotics powerless.
Naltrexone reduces both the. The rationale was to completely shut off the high of abused narcotics.
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